I found William Powell hilarious in his alcoholic (but sharp witted) role (lovable like Dudley Moore in Arthur but calculating like Sherlock Holmes) and I thought Myrna Loy was gorgeous (especially her nose which I found uniquely cute). And who could forget the Adorable Dog ASTA who even has his own fan site! http://www.iloveasta.com/ThinMan.htm. As the site sums up..."Endless cocktails and abundant wealth aside, Nick and Nora Charles presented a picture of the kind of married domestic life people really wanted - and still want - to have."
I should also mention that the story was based on a 1933 book written by the amazing Dashiell Hammett.